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Subject:
From:
"Nice, Frank" <[log in to unmask]>
Reply To:
Lactation Information and Discussion <[log in to unmask]>
Date:
Wed, 3 Jun 1998 09:22:23 -0400
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There has been previous discussion on Lactnet regarding the use of Trovan while
breastfeeding to which I refer you.
I want  to add some additional information from the drug manufacturer:
"Trovafloxacin was found in measurable concentrations in the breast milk of
three lactating subjects.  The average measurable breast milk concentration was
0.8 ug/mL (range: 0.3-2.1 ug/mL) after single I.V. alatrofloxacin (300 mg
trovafloxacin equivalents) and repeated oral trovafloxacin (200 mg) doses."
NOTE: The manufacturer states that " the safety and effectiveness of
trovafloxacin in pediatric populations less than 18 years of age, pregnant
women, and nursing women has not been established."

Frank J. Nice, DPA, CPHP

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