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Lactation Information and Discussion <[log in to unmask]>
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Fri, 6 Mar 1998 15:25:53 +0000
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Good summary.  I should point out that a fat soluble drug can still be
highly protein bound and thus not pass readily into the milk.  The way
you wrote it, it sounds as if the two are mutually exclusive.

The usual situation that I see at least, of women "requiring" oral
hypoglycemics is that their blood sugars are taking a while to come down
after delivery.  Women in the reproductive age group only very
occasionally have the sort of diabetes requiring oral hypoglycemics.
Thus, the oral hypoglycemics are ordered because the physician has pity
on the mother and decides it is better to give oral hypoglycemics than
continue insulin which the mother used during pregnancy.  However, the
requirement for hypoglycemic medication is usually very short (weeks at
the most), and thus, I usually suggest the mothers continue insulin
rather than fiddling with oral hypoglycemics.  Thus they don't have to
worry about these drugs and whether they can breastfeed.

Jack Newman, MD, FRCPC

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