Title: Lactose malabsorption in young Lithuanian children with atopic
dermatitis

Author(s): O Rudzeviciene ; I Narkeviciute ; R Eidukevicius

Source: Acta Paediatrica
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Volume: 93 Number: 4 Page: 482 -- 486 DOI: 10.1080/08035250410024754
Publisher:Taylor & Francis Health Sciences

Abstract: Aim: To determine the prevalence of lactose malabsorption in
young Lithuanian atopic dermatitis children; to evaluate the
relationship between lactose malabsorption and the duration of exclusive
breastfeeding, and the relationship between lactose malabsorption and
cow's milk intolerance in parents and grandparents. Methods: 144
children with atopic dermatitis aged 1.5-24 mo (study group) and 32
children without symptoms of allergic diseases aged 1.5-23 mo (control
group) were investigated. Lactose and glucose-galactose absorption tests
based on serial blood glucose determination, culture of stool, latex
agglutination test for rotavirus and microscopic examination of stool
for parasites were performed. Results: Lactose malabsorption was
determined in 59 (40.9%) and glucose-galactose malabsorption in 17
(11.8%) children with atopic dermatitis. The risk of developing lactose
malabsorption was higher in children fed exclusively on breast milk up
to 1 mo of age than in children fed exclusively on breast milk for 4 to
6 mo (OR: 2.62; 95% CI: 1.02-6.75). Lactose malabsorption was
significantly more frequent in patients whose mothers did not tolerate
cow's milk (20/30; 66.7%) than in patients whose mothers were tolerant
to it (39/95; 41.1%) (p = 0.02).
Conclusion: Lactose malabsorption was determined in 40.9% of Lithuanian
atopic dermatitis children aged under 2 y. Lactose malabsorption
appeared to be associated with the duration of exclusive breastfeeding
up to only 1 mo and mothers' milk intolerance.


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