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Subject:	Clonazepam for Post Partum "Anxiety"
From:	"Frank J. Nice" <[log in to unmask]>
Reply To:	Lactation Information and Discussion <[log in to unmask]>
Date:	Fri, 22 Jun 2018 12:49:50 +0000
Content-Type:	text/plain
Parts/Attachments:	text/plain (29 lines)

I apologize for the incorrect subject line.  I meant anxiety, not depression.





Clonazepam is a terrible choice for postpartum anxiety, especially with drowsiness side effect already occurring, because of its extremely long half-life, whereby it can start accumulating over time, so timing breastfeeding and dosing will not work well.

A much better choice would be buspiron (Buspar), which has much better pharmacokinetics for breastfeeding, especially much shorter half-life.

PS: Freezing does not affect drug potency.



Frank J. Nice, RPh, DPA, CPHP



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