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Subject:
From:
Magda Sachs <[log in to unmask]>
Reply To:
Lactation Information and Discussion <[log in to unmask]>
Date:
Mon, 27 Sep 1999 13:23:12 GMT
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Sharon, I have looked at Cousoudis et al again (this is the research paper I
think you are refering to in your post) and they summarise their findings:

Findings At 3 months, 18·8% (95% CI 12·6-24·9) of 156 never-breastfed children
were estimated to be HIV-1 infected compared with 21·3% (17·2-25·5) of 393
breastfed children (p=0·5). The estimated proportion (Kaplan-Meier) of infants
HIV-1 infected by 3 months was significantly lower for those exclusively
breastfed to 3 months than in those who received mixed feeding before 3 months
(14·6% [7·7-21·4] vs 24·1% [19·0-29·2], p=0·03). After adjustment for potential
confounders (maternal CD4-cell/CD8-cell ratio, syphilis screening test results,
and preterm delivery), exclusive breastfeeding carried a significantly lower
risk of HIV-1 transmission than mixed feeding (hazard ratio 0·52 [0·28-0·98])
and a similar risk to no breastfeeding (0·85 [0·51-1·42]).

I am not sure what paper you posted the abstract of, but this above is the paper
which shows the similar rate of mother-to-child trnasmission of HIV with either
exclusive breastfeeding or exclusive replacement feeding.  full ref:Coutsoudis,
et al, Influence of infant-feeding  patterns on early mother-to-child
transmission of HIV-1 in Durban, South Africa:  a prospective cohort study, The
Lancet v354 7 August 1999

They defined bexclusive breastfeeding not jsut as no other milks but that 'no
other liquids, including water, or food had been given to the child before 3
months of age'

Hope this helps.

Full url:
http://www.thelancet.com/newlancet/reg/issues/vol354no9177/early471.html


Magda Sachs Breastfeeding Supporter
BfN, UK

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