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Subject:
From:
"Jan Ellen Brown RDH, IBCLC" <[log in to unmask]>
Reply To:
Lactation Information and Discussion <[log in to unmask]>
Date:
Thu, 21 Jan 1999 18:19:14 EST
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Dear Janette,
    In your post about pancreatic enzymes, I ssume this is for maternal
ingestion?  If so, I have had some experience with pancreatic enzymes of
vegetable/plant derivitives and/or bovine and pork derivitives.  Patients with
cystic fibrosis and pancreatic insufficiency require enzymes for digestion.
The standard dosage is titrated on lipase per kg and can vary from patient to
patient depending on steatorrhea, gas and weight gain.  I had my daughter on a
plant derivitive (OTC) along with standard Pancrease or Creon (prescription,
because this is an "orphan disease" plus insurance coverage).  The plant type
was supposedly easier to "digest" but it stands to reason the enteric coated
prescriptions withstand the acid ph of the stomach and aid in better digestion
.....a few years ago there was a warning of  colon lining fibrosis but that
was demonstated in very, very high dosages.  It did ,however, lead to a
reduction of capsules with high levels of lipase, amylase and protease.  Also
taking Zantac with them, the H2 histamine receptor blockers (cimetidine and
ranitidine) ,can reduce gastric acid secretion and have been effective for
some patients in increasing body weight and reducing stool and nitrogen, but
their long term safety and efficacy is not reported.  I have witnessed no
problems associated with pancreatic enzymes taken by lactating mothers.
    Please feel free to contact me about this.  I have the library on CF and
pancreas issues at my fingertips!

Jan Ellen Brown RDH IBCLC
Charlotte, NC USA
PS.  A few years ago I donated some expired enzymes to a veterinary clinic for
use with animals with pancreatitis!

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