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Subject:
From:
"Valerie W. McClain, IBCLC" <[log in to unmask]>
Reply To:
Lactation Information and Discussion <[log in to unmask]>
Date:
Wed, 5 Jul 2000 05:10:40 EDT
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text/plain
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I would encourage women to eat a healthy diet rather than resort to
supplements of DHA.  I have concerns about DHA and thought you all might be
interested in reading a patent on DHA.  Patent # 5711983

"Any microorganisms capable of producing a single-cell edible oil containing
DHA can be used in the present invention. For example, photosynthetic diatoms
can be used. Preferred microorganisms are marine dinoflagellates, including
Crypthecodinium sp. Especially preferred is Crypthecodinium cohnii, an
obligate heterotroph requiring a reduced carbon source for growth. C. cohnii
is preferred because it contains a fatty acid profile in which DHA is the
only PUFA present in sufficient quantities (greater than about 1% of the
total amount of PUFAs). Samples of this organism, designated MK8840, have
been deposited with the American Type Culture Collection at Rockville, Md.,
and assigned accession number 40750. As used herein, microorganism, or any
specific type of microorganism, includes wild strains, mutants or recombinant
types. Any microorganism which produces enhanced levels of oil containing DHA
is considered to be within the scope of this invention. One of the features
of the present invention is its recognition of the edible oil-producing
capability of microorganisms such as dinoflagellates and the attendant
solution to the problem of maintaining a reliable, economic source of such
oils. Accordingly, wild-type and recombinant microorganisms designed to
produce single cell oil containing DHA are an aspect of this invention. Such
recombinant organisms would include those designed to produce greater
quantities of DHA in the single cell oil, greater quantities of total oil, or
both, as compared to the quantities produced by the same wild type
microorganism, when provided with the same substrates. Also included would be
microorganisms designed to efficiently use more cost-effective substrates
while producing the same amount of single cell oil containing DHA as the
comparable wild-type microorganism."

Pleasenote the word recombinant in this patent.  Valerie W. McClain, IBCLC

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