This was reported in my medscape newsletter this week:
Phase I Trials of Newborn HIV Vaccine Set to Begin in October
FLORENCE, Italy (Reuters Health) Jun 26 -- A phase I trial to evaluate a
vaccine that could prevent HIV infection in newborns during breast-feeding
will begin at the end of October, top HIV researchers announced on Tuesday
at an international meeting in Rome organized by the Italian Parliament's
Culture Commission.
Created by the UNESCO-supported World Foundation for AIDS Research and
Prevention, the "Families First Africa" pediatric vaccine initiative will
eventually be carried out in Africa, where each year about 600,000 newborns
are infected by their mothers. The post-exposure vaccine, which consists of
synthetic HIV peptides incorporated into the tuberculosis vaccine BCG, is
the work of Dr. Robert Gallo, director of the Institute of Human Virology in
Baltimore, Maryland, Dr. Luc Montagnier, president of the World Foundation
for AIDS, and Dr. Vittorio Colizzi, of Rome's Tor Vergata University.
Phase I trials involving 30 healthy volunteers should begin at the end of
October in Baltimore.
"By the first months of 2004 we should be able to start phase I clinical
trials on newborns in the West African countries of Burkina Faso, Cameroon
and Ivory Coast. We hope to be able to report the first results by June
2004," Dr. Colizzi told Reuters Health.
The Italian government has committed 2 million dollars to fund the program.
Laurie Wheeler, IBCLC, MN, RN
New Orleans Louisiana, s.e. USA
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