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Subject:
From:
"Valerie W. McClain, IBCLC" <[log in to unmask]>
Reply To:
Lactation Information and Discussion <[log in to unmask]>
Date:
Thu, 5 Dec 2002 14:41:16 EST
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Marsha, 

I found this at a CDC web site in regard to the TRIGR study:  It looks to me 
like the non-intervention group is being given standard cow's milk based 
formula versus the breastfed/hydrolysed formula group.  I do believe that one 
might suspect that this new hydrolysed formula might just be a gene altered 
cow's milk formula.  No proof, but cloned milk is now GRAS, so I am a bit 
suspicious.  Valerie W. McClain, IBCLC

http://www.cdc.gov/genomics/hugenet/reviews/diabetes.htm

Population Testing
<I style="mso-bidi-font-style: normal">Screening in Families   

At present, there is no cure for type 1 diabetes, and lifelong insulin 
therapy is the only available treatment.  However, several large clinical 
trials have begun to evaluate a variety of primary and secondary 
interventions in family members.  Eligible persons are identified from 
families of affected probands using one of two general strategies.  The first 
involves screening for high risk HLA-DQ alleles.   The Trial to Reduce Type 1 
Diabetes in the Genetically At-Risk (TRIGR) screens newborns for DQB1*0302, 
DQB1*0201, DQB1*0602/3 and DQB1*0301 (83).  Although this approach does not 
permit exact genotyping, it can be used to identify individuals at high risk 
(i.e., positive for DQB1*0302 and / or DQB1*0201) and low risk (i.e., 
positive for DQB1*0602/3 and / or DQB1*0301) for purposes of inclusion and 
exclusion, respectively.   Those at high risk are eligible for randomization. 
 In TRIGR, the intervention group receives a casein hydrolysate formula, and 
/ or breast milk for the first six months of life.  In contrast, the control 
group receives a typical cow’s milk formula."





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