Lisa,
Your mother's major issue is that she is not producing prolactin, which is
part of the substrate for lactose synthesis, which drives milk
production/volume. Oxytocin for milk ejection is a moot point if there is no
milk. Because her pituitary is severely damaged, hormonal deficiencies
usually must be replaced; the usual stimulatory medications don't have much
effect. In Russia and eastern Europe they actually have animal recombinant
prolactin that is available commercially, but here we are experimenting with
human versions. 

Your client might be a good candidate for a study being done with human
recombinant prolactin. Corrine Welt, MD, is working out of Massachusetts
General Hospital in Boston. Her contact info as posted online: 617-726-8437
[log in to unmask]   You might contact her first to see if your client
qualifies before raising any hopes.

The onset of Sheehan's can be quick or gradual. Sometimes improvement
occurs, but other times the mother's condition deteriorates. As always, each
case is different.

~Lisa Marasco

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