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From:
Holly MCSPADDEN <[log in to unmask]>
Reply To:
Lactation Information and Discussion <[log in to unmask]>
Date:
Sun, 31 Jan 2010 19:11:50 -0800
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Hi Marianne,
 
Have you seen this article? It summarizes most of the major research on Oxytocin.
 
Holly McSpadden, IBCLC
 
1. Prog Neurobiol. 2009 Jun;88(2):127-51. Epub 2009 Apr 10.

Oxytocin: the great facilitator of life.

Lee HJ, Macbeth AH, Pagani JH, Young WS 3rd.

Section on Neural Gene Expression, NIMH, NIH, DHHS, Bethesda, MD 20892, USA.

Oxytocin (Oxt) is a nonapeptide hormone best known for its role in lactation and 
parturition. Since 1906 when its uterine-contracting properties were described
until 50 years later when its sequence was elucidated, research has focused on
its peripheral roles in reproduction. Only over the past several decades have
researchers focused on what functions Oxt might have in the brain, the subject of
this review. Immunohistochemical studies revealed that magnocellular neurons of
the hypothalamic paraventricular and supraoptic nuclei are the neurons of origin 
for the Oxt released from the posterior pituitary. Smaller cells in various parts
of the brain, as well as release from magnocellular dendrites, provide the Oxt
responsible for modulating various behaviors at its only identified receptor.
Although Oxt is implicated in a variety of "non-social" behaviors, such as
learning, anxiety, feeding and pain perception, it is Oxt's roles in various
social behaviors that have come to the fore recently. Oxt is important for social
memory and attachment, sexual and maternal behavior, and aggression. Recent work 
implicates Oxt in human bonding and trust as well. Human disorders characterized 
by aberrant social interactions, such as autism and schizophrenia, may also
involve Oxt expression. Many, if not most, of Oxt's functions, from social
interactions (affiliation, aggression) and sexual behavior to eventual
parturition, lactation and maternal behavior, may be viewed as specifically
facilitating species propagation.

PMCID: PMC2689929 [Available on 2010/6/1]
PMID: 19482229 [PubMed - indexed for MEDLINE]


--- On Sun, 1/31/10, Marianne Vanderveen-Kolkena <[log in to unmask]> wrote:


From: Marianne Vanderveen-Kolkena <[log in to unmask]>
Subject: Niles Newton
To: [log in to unmask]
Date: Sunday, January 31, 2010, 5:15 PM


Hi all,

After finishing Aletha Solters book (with really weird statements on breastfeeding... :-s), I picked up 'Impact of Birthing Practices' again, by Mary Kroeger (and Linda S.).
She writes about Niles Newton's groundbreaking work on oxytocin, called 'Maternal Emotions'.
Does anyone have or know this book? Is it worth buying?
It seems like a classic on oxytocin, which I'm really interested in.
Your opinions will be very much appreciated!

Bye,

Marianne Vanderveen IBCLC, Netherlands

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