To Kris Rogers:

Metrodin is urofollitropin,  a preparation of gonadotropins extracted from
the urine of postmenopausal women.  It is a purified preparation of
follicle stimulation hormone (FSH).   FSH is the normal gonadotropin that
stimulates the production of ovarian follicles.  FSH has 2 half-lives, 3.9
hours, and 70.4 hours. FSH is a large molecular weight peptide (34,000
daltons) that is too large to be secreted into milk,  and would most
certainly not be orally absorbed by an infant.

As to whether FSH would inhibit lactation, is another question.  Metrodin
is given in differing doses.  It is given in smaller doses to induce
follicle production for in vivo insemination.  For in vitro fertilization,
where numerous ovum are required, very high doses of FSH are required. The
importance of this is that as the number of follicles increase, so does the
maternal estrogen levels.  Remember, it is estrogen that suppresses
lactation significantly.

It would be my guess, depending on the dose,  that Metrodin would
ultimately suppress lactation by stimulating endogenous estrogen levels.
It would not one the other hand pass to the infant via milk.

Tom Hale