LACTNET Archives

Lactation Information and Discussion

LACTNET@COMMUNITY.LSOFT.COM

Options: Use Forum View

Use Monospaced Font
Show Text Part by Default
Show All Mail Headers

Message: [<< First] [< Prev] [Next >] [Last >>]
Topic: [<< First] [< Prev] [Next >] [Last >>]
Author: [<< First] [< Prev] [Next >] [Last >>]

Print Reply
Subject:
From:
"Dr. Tom Hale" <[log in to unmask]>
Reply To:
Lactation Information and Discussion <[log in to unmask]>
Date:
Mon, 8 Jun 1998 18:18:44 -0400
Content-Type:
text/plain
Parts/Attachments:
text/plain (44 lines)
To : Ann
Re : Loss of libido

As per the mom taking gingko and Paxil.  Loss of libido is a major problem
with virtually all serotonin reuptake inhibitor antidepressants. This is
normal for this drug.  Nothing you can do about it.

As for lithium and pregnancy, a number of congenital defects including
Ebsteins anomaly is well described for this drug, although it is rare and
controversial.  The risks are higher during the first trimester.

Breastfeeding with lithium is controversial. Some say yes, others no.  It is
probably ok if the mom and infant are periodically checked for lithium
levels.  Expect that the lithium level in the infant will be about 30-40% of
moms.  I would also suggest a thyroid exam for the infant as hypothyroidism
with lithium therapy is well documented.

--------------------
To : Lisa
Re : Azathioprine

Azathioprine is really risky for a breastfeeding pair, and I would suggest,
as Dr. Newman,  that perhaps the mom could be managed with prednisone for a
while and try to stay away from azthioprine.

--------------------------------
To : Marsha
Re : Claritin

From my '98 book:
Loratadine is a long-acting antihistamine with minimal sedative properties.
Milk:plasma ratios for loratadine and its active metabolite are 1.17 and
0.85 respectively.  Following a single oral dose of 40 mg a small amount of
loratadine and metabolite were transferred into human milk  (approximately
0.029% over 48 hrs).  Loratadine does not transfer into the CNS of adults.
The half-life in neonates is not known although it is likely quite long.
Pediatric formulations are available.   AHL=  8.4 hrs (loratadine),  28 hrs
(metabolite).


Regards

Tom Hale, Ph.D.

ATOM RSS1 RSS2