On 3/21/05 9:26 AM, "Mellanie" <[log in to unmask]> wrote:
> I had a mother call this morning who has just been told she carries HTLV-1
> virus. She had a baby 6 months ago, stored the baby's cord blood and has
> just now been contacted by the cord blood storage company and told they
> found the HTLV-1 virus in the cor blood. She is very angry that she is just
> being given this information. She has been told to stop breastfeeding
> immediately. She is going to rent a pump and begin pumping and storing her
> milk. I found reference to a 1989 study indicating that the HTLV-1 virus
> may be inactivated by freezing breastmilk. I searched the archives but
> could find no other info. Needless to say, this mother is devastated. I
> would like to be able to give her all of the info I can. Thanks for any
> help you can give.
Latrobe's web site says:
"
€ HTLV-1 (all cell-associated) is destroyed within 20 minutes at
56°C (or 10 minutes at 90°C), or by freezing at -20°C for 12 hours. Cell
associated HIV provirus DNA is destroyed by bringing milk to the boil.
Boiling milk destroys the immunoglubulins, lactoferrin, lysozyme and the
milk's bacteriostaic activity, but not the peptide beta defensin-1."
From "Molecular Virology: Tables of Antimicrobial Factors and Microbial
Contaminants in Human Milk
Table 7: Effect of heat treatment or storage on antimicrobial factors in
human milk"
http://www.latrobe.edu.au/microbiology/table7.html
The extensive bibliography for the table is here:
http://www.latrobe.edu.au/microbiology/milkbib7.html
And includes this cite:
" Ando Y., Ekuni Y., Matsumoto Y., Nakano S., Saito K., Kakimoto K.,
Tanigawa T., Kawa M., and Toyama T. (2004) Long-term serological outcome of
infants who received frozen-thawed milk from human T-lymphotropic virus
type-1 positive mothers. J. Obstet. Gynaecol. Res., 30, 436-438."
-- Jodine Chase
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