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Lactation Information and Discussion <[log in to unmask]>
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Fri, 19 Oct 2012 10:17:36 -0500
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I wish these promoters could have heard some of the research on gene expression.  Only human milk facilitates expression of one of the genes responsible for intelligence.  No formula anywhere will be able to do that.  Period.  If anyone spent as much money on helping women breastfeed an overcoming the obstacles - which go from iatrogenic to economic to societal to genetic - and spent the rest of the money on promoting human milk banking - we would be so much further along!

-----Original Message-----
From: Lactation Information and Discussion [mailto:[log in to unmask]] On Behalf Of Nikki Lee
Sent: Thursday, October 18, 2012 7:22 AM
Subject: latest from our competitors' research

Dear Lactnet Friends:

And the expensive and wasteful effort to create human milk in a can continues............

BMC Pediatr. <http://www.ncbi.nlm.nih.gov/pubmed/23072617#> 2012 Oct 17;12(1):164.
The influence of a formula supplemented with dairy lipids and plant oils on the erythrocyte membrane omega-3 fatty acid profile in healthy full-term
infants: a double-blind randomized controlled trial.
Giannì ML<http://www.ncbi.nlm.nih.gov/pubmed?term=ann%C3%AC%20ML%5BAuthor%5D&cauthor=ue&cauthor_uid#072617>
, Roggero P<http://www.ncbi.nlm.nih.gov/pubmed?term=ggero%20P%5BAuthor%5D&cauthor=ue&cauthor_uid#072617>
, Baudry C<http://www.ncbi.nlm.nih.gov/pubmed?termºudry%20C%5BAuthor%5D&cauthor=ue&cauthor_uid#072617>
, Ligneul A<http://www.ncbi.nlm.nih.gov/pubmed?term=gneul%20A%5BAuthor%5D&cauthor=ue&cauthor_uid#072617>
, Morniroli D<http://www.ncbi.nlm.nih.gov/pubmed?term=rniroli%20D%5BAuthor%5D&cauthor=ue&cauthor_uid#072617>
, Garbarino F<http://www.ncbi.nlm.nih.gov/pubmed?term=rbarino%20F%5BAuthor%5D&cauthor=ue&cauthor_uid#072617>
, Ruyet P<http://www.ncbi.nlm.nih.gov/pubmed?term=yet%20P%5BAuthor%5D&cauthor=ue&cauthor_uid#072617>
, Mosca F<http://www.ncbi.nlm.nih.gov/pubmed?term=sca%20F%5BAuthor%5D&cauthor=ue&cauthor_uid#072617>
.
 AbstractABSTRACT:

BACKGROUND: Human milk is the optimal nutrition for infants. When breastfeeding is not possible, supplementation of infant formula with long chain polyunsaturated fatty acids appears to promote neurodevelopmental outcome and visual function. Plant oils, that are the only source of fat in most of infant formulas, do not contain specific fatty acids that are present in human and cow milk and do not encounter milk fat triglyceride structure. Experimental data suggest that a mix of dairy lipids and plant oils can potentiate endogenous synthesis of n-3 long chain polyunsaturated fatty acids. This trial aims to determine the effect of an infant formula supplemented with a mixture of dairy lipids and plant oils on the erythrocyte membrane omega-3 fatty acid profile in full-term infants (primary outcome). Erythrocyte membrane long chain polyunsaturated fatty acids and fatty acids content, the plasma lipid profile and the insulin-growth factor 1 level, the gastrointestinal tolerance, the changes throughout the study in blood fatty acids content, in growth and body composition are evaluated as secondary outcomes.
METHODS:

In a double-blind controlled randomized trial, 75 healthy full-term infants are randomly allocated to receive for four months a formula supplemented with a mixture of dairy lipids and plant oils or a formula containing only plant oils or a formula containing plant oils supplemented with arachidonic acid and docosahexaenoic acid. Twenty-five breast-fed infants constitute the reference group. Erythrocyte membrane omega-3 fatty acid profile, long chain polyunsaturated fatty acids and the other fatty acids content, the plasma lipid profile and the insulin-growth factor 1 level are measured after four months of intervention. Gastrointestinal tolerance, the changes in blood fatty acids content, in growth and body composition, assessed by means of an air displacement plethysmography system, are also evaluated throughout the study.
DISCUSSION:

The achievement of an appropriate long chain polyunsaturated fatty acids status represents an important goal in neonatal nutrition. Gaining further insight in the effects of the supplementation of a formula with dairy lipids and plant oils in healthy full-term infants could help to produce a formula whose fat content, composition and structure is more similar to human milk. Trial registration ClinicalTrials.gov Identifier NCT01611649.

warmly,
Nikki Lee RN, BSN, Mother of 2, MS, IBCLC, CCE, CIMI, ANLC, CKC craniosacral therapy practitioner www.breastfeedingalwaysbest.com https://www.facebook.com/nikkileehealth

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