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Subject:
From:
Tom Hale <[log in to unmask]>
Reply To:
Lactation Information and Discussion <[log in to unmask]>
Date:
Mon, 23 Sep 1996 13:26:41 -0500
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To      :Laura Walker
Re      :Typhoid vaccine, cholera vaccine, Atenolol

Typhoid vaccine is a live attenuated bacterial culture of a specific strain of
typhoid.  Although there are no indications for use or studies in breastfeeding
mothers,  the vaccine is cleared for use in infants down to the age of 6
months.  Being bacterial, I would doubt its entry into breastmilk nor any major
complications in a breastfeeding infant.  It would not be advisable, obviously,
to use in an mother/infant pair who are ill, or immunocompromised in any way.

As for cholera vaccine,  it is a phenol killed bacterial vaccine that can
actually boost the anticholera immunoglobulins secreted into milk.  It is also
used in infants down to 6 months of age.  It is unlikely to adversely effect a
breastfeeding infant.

As for using Tenormin (atenolol) in breastfeeding mothers.  I am somewhat
nervous about this product as several cases of bradycardia and cyanosis have
been reported.  It appears highly variable.  Perhaps the physician would
consider changing to Inderol (propranolol),  which is quite effective, and
produces very poor milk levels.

Regards
Tom Hale, Ph.D.

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