Nitrous is contraindicated in anyone with MTHFR as it caused an elevation in homocysteine. That's almost half the human population at this point and that could be the mother or the baby. Another epigenetic methylation nightmare in the making. 


Anesthesiology. 2008 Jul;109(1):36-43. doi: 10.1097/ALN.0b013e318178820b.
Influence of methylenetetrahydrofolate reductase gene polymorphisms on homocysteine concentrations after nitrous oxide anesthesia.

BACKGROUND:
Mutations in the methylenetetrahydrofolate reductase (MTHFR) gene (677C>T, 1298A>C) cause elevated plasma homocysteine concentrations and have been linked to fatal outcomes after nitrous oxide anesthesia. This study tested the hypothesis that patients with common MTHFR 677C>T or 1298A>C mutations develop higher plasma homocysteine concentrations after nitrous oxide anesthesia than wild-type patients.
CONCLUSIONS:
This study shows that patients with a homozygous MTHFR 677C>T or 1298A>C mutation are at a higher risk of developing abnormal plasma homocysteine concentrations after nitrous oxide anesthesia.


http://www.ncbi.nlm.nih.gov/pubmed/18580170


Jennifer Tow, IBCLC, USA & France
Intuitive Parenting Network, LLC




Date:    Sun, 11 Jan 2015 15:15:34 -0500
From:    Lori Atkins <[log in to unmask]>
Subject: Breastfeeding effects from intrapartum Nitrous use?

Hello, wise lactnet ladies!

Looking for any better ( than the little I've seen ) studies or information on 
breastfeeding effects from the use of Nitrous Oxide for labor pain/analgesia. We 
have an early hospital committee looking into it's use. I know its been used for 
years in Great Britain, but I can't seem to find a ton of great research on 
breastfeeding effects. Thoughts? Thanks so much in advance.

Lori Atkins, RN, IBCLC

  

 

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