LACTNET Archives

Lactation Information and Discussion

LACTNET@COMMUNITY.LSOFT.COM

Options: Use Forum View

Use Monospaced Font
Show Text Part by Default
Show All Mail Headers

Message: [<< First] [< Prev] [Next >] [Last >>]
Topic: [<< First] [< Prev] [Next >] [Last >>]
Author: [<< First] [< Prev] [Next >] [Last >>]

Print Reply
Subject:
From:
Reply To:
Lactation Information and Discussion <[log in to unmask]>
Date:
Wed, 17 Mar 1999 23:53:16 EST
Content-Type:
text/plain
Parts/Attachments:
text/plain (21 lines)
Rob,

The reference I used that stated phenergan was an antihistamine (primary
mechanism of action):
Gellis and Kagan, Current Pediatric Therapy, volume 15, page 267-(1996)
A respected pediatric pharmacotherapeutic text.  Oops it is also a
phenothiazine (quick check in my Harriet Lane Handbook).  I unfortunately
don't have Hale and my pharm books are from the 80's-very musty .

I think the other risk aspect that separates phenergan from the drugs such as
prochlormeperazine and other dopamine antagonists is that the latter drugs
also lower seizure threshold (another nasty side effect).  I think that's the
other reason why proponents of promethazine (phenergan) prefer it over the
dopamine antagonist classes  of antiemetics.  I'm not a great fan of phenergan
but use it sparingly in kids over 2 (and only for the antiemetic and
antinausea indication never for cough suppression as others do).

Thanks for the check!

Mimi

ATOM RSS1 RSS2