Jessica and Others:  The University of Illinois Perinatal Depression Project has 
a nice one-page handout arranged in table form that lists all the current anti-
depressants.  The headings are "advantages during 
pregnancy", "disadvantages during pregnancy" "percent of dose to the 
breastfed baby", "reported side effects", and "tetratogenicity".  You should be 
able to access this information via the website:  
www.psych.uic.edu/clinical/HRSA.
I know and have worked with 1 of the major researchers on this project and 
have referred to her many times over the years.  Her co-worker recently had a 
baby at my hospital and when the subject came up, I mentioned how useful I 
have been finding this table - turns out she developed the table!  She told me 
the plan was to update the table as information changes.  I laminated copies 
and placed them on each of our units as well as the neonatology office for the 
medical/nursing staff use.
To answer your question, Jessica, this group recommends Zoloft as the drug of 
choice if mom is breastfeeding.  Prozac is the drug of choice during 
pregnancy - if mom is not planning on breastfeeding, it is recommended that 
she stay on Prozac.  Otherwise, the recommendation is she be switched from 
Prozac to Zoloft, if breastfeeding.


Pam Hirsch, BSN,RN,IBCLC
Clinical Lead, Lactation Services
Advocate Good Shepherd Hospital
Barrington, IL   USA

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