Interactions of fetal experience and later diet may lead to disease,
according to this hypothesis:

                  National Library of Medicine MEDLINE Database


TITL: Maternal and fetal determinants of adult diseases. 58 REFS

AUTH: Goldberg GR; Prentice AM

ORGA: MRC Dunn Clinical Nutrition Centre, Cambridge, UK.

CITE: Nutr Rev 1994 Jun; 52 (6): 191-200


ABST: Recent epidemiologic studies in the United Kingdom have led to the
hypothesis that adverse nutritional experiences in utero have a powerful
influence on the development of degenerative diseases in adulthood. Poor fetal
growth as measured by weight, length, head, chest, and abdominal circumferences
is a strong predictor of hypertension,  diabetes,  hyperlipidemia, alteration in
clotting factors, Syndrome X,* and mortality from cardiovascular and chronic
obstructive airways disease. The theory of fetal origins of adult disease
proposes that early defects in the development, structure, and function of
organs lead to a programmed susceptibility, which interacts with later  diet
and environmental stresses to  cause  overt disease many decades after the
original insult. (AUTHOR)

MJTR: Cardiovascular Diseases MO.    Fetal Development.    Models, Biological.
   Nutrition.

MNTR: Birth Weight.    Cardiovascular Diseases ET.    Cause of Death.
   Cholesterol BL.     Diabetes  Mellitus, Non-Insulin-Dependent ET.    England.
   Female.    Follow-Up Studies.    Human.    Lung Diseases ET.    Male.
   Middle Age.    Nutritional Status.    Retrospective Studies.    Syndrome.
JOURNAL ARTICLE. REVIEW. REVIEW, TUTORIAL

RNUM: 57-88-5 (Cholesterol)

GEOT: UNITED STATES

IDEN: ISSN:  0029-6643. JOURNAL-CODE:  OAY. ENTRY-DATE:  950424. IM-DATE:  9506.

ACCE: 95206620





Arly Helm                                       [log in to unmask]