About itraconazole :
99% bound to plasmatic proteins
Half life : 15 to 20 hours
Maximum level in milk after 4 hours

Pediatric dose : 3 to 10 mg/kg/day
One study on 2 women, who were given two doses of 200 mg in one day. Maximum
level in milk : 0,088 mg/l. Maximum absorption by the child : 0,02
mg/kg/jour. Nos studied after long term treatment, possibility of
accumulation in milk.

Kindly
Françoise Railhet
LLL France Medical Associates Program
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