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Subject:
From:
Janet Simpson <[log in to unmask]>
Reply To:
Lactation Information and Discussion <[log in to unmask]>
Date:
Thu, 1 Aug 1996 19:29:20 -0400
Content-Type:
text/plain
Parts/Attachments:
text/plain (29 lines)
Hi!
Straight from the new Tom Hale:

DIFLUNISAL

Trade:  Dolobid
Uses:  Nossteroidal anti-inflammatory analgesic
AAP:  Not Reviewed

Diflunisal is a derivative of salicylic acid.  Diflunisal is excreted into
human milk in concentrations of 2-7% of the maternal plasma levels.  No
reprts of side-effects have been located.  This product is potentially a
higher risk NSAID and other less toxic compounds should be used.  Because it
is a derivative of slicylic acid, an increased risk of Reyes syndrome cannot
be excluded.  See ibuprofin as an alternative.

Adverse effects:  Prolonged bleeding time, headache, GI distress, diarrhea,
GI cramping

AHL= 8-12 hours                    M/P=
PHL=                                    PB= 99%
PK=2-3 hours                         Oral= Complete



Hope this helps!
Jay
Who is loving her Hale!

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