LACTNET Archives

Lactation Information and Discussion

LACTNET@COMMUNITY.LSOFT.COM

Options: Use Forum View

Use Monospaced Font
Show Text Part by Default
Show All Mail Headers

Message: [<< First] [< Prev] [Next >] [Last >>]
Topic: [<< First] [< Prev] [Next >] [Last >>]
Author: [<< First] [< Prev] [Next >] [Last >>]

Print Reply
Subject:
From:
Magda Sachs <[log in to unmask]>
Reply To:
Lactation Information and Discussion <[log in to unmask]>
Date:
Fri, 16 Feb 2001 16:28:45 -0000
Content-Type:
text/plain
Parts/Attachments:
text/plain (55 lines)
Just thought you all might like to see.  This journal no longer free access
on-line, so I have not seen the full study yet.

Magda Sachs
Breastfeeding Supporter, BfN, UK

Coutsoudis A et al. Method of feeding and transmission of HIV-1 from
mothers to children by 15 months of age: prospective cohort study
from Durban, South Africa. AIDS. 2001 Feb 16; 15(3): 379-87.

ABSTRACT

OBJECTIVE: To determine the risk of HIV transmission by infant
feeding modality.

DESIGN AND SETTING: A prospective study in two hospitals in Durban,
South Africa.

PARTICIPANTS: A total of 551 HIV-infected pregnant women enrolled in
a randomized trial of vitamin A.

INTERVENTIONS: Women self-selected to breastfeed or formula feed
after being counselled. Breastfeeders were encouraged
to practice exclusive breastfeeding for 3--6 months.

MAIN OUTCOME MEASURES: Cumulative probabilities of detecting HIV over
time were estimated using Kaplan--Meier
methods and were compared in three groups: 157 formula-fed (never
breastfed); 118 exclusively breastfed for 3 months or more;
and 276 mixed breastfed.

RESULTS: The three feeding groups did not differ in any risk factors
for transmission, and the probability of detecting HIV at
birth was similar. Cumulative probabilities of HIV detection remained
similar among never and exclusive breastfeeders up to 6
months: 0.194 (95% CI 0.136--0.260) and 0.194 (95% CI 0.125--0.274),
respectively, whereas the probabilities among mixed
breastfeeders soon surpassed both groups reaching 0.261 (95% CI
0.205--0.319) by 6 months. By 15 months, the cumulative
probability of HIV infection remained lower among those who
exclusively breastfed for 3 months or more than among other
breastfeeders (0.247 versus 0.359).

CONCLUSION: Infants exclusively breastfed for 3 months or more had no
excess risk of HIV infection over 6 months than
those never breastfed. These findings, if confirmed elsewhere, can
influence public health policies on feeding choices available to
HIV-infected mothers in developing countries.

             ***********************************************
The LACTNET mailing list is powered by L-Soft's renowned
LISTSERV(R) list management software together with L-Soft's LSMTP(TM)
mailer for lightning fast mail delivery. For more information, go to:
http://www.lsoft.com/LISTSERV-powered.html

ATOM RSS1 RSS2