Subject: | |
From: | |
Reply To: | |
Date: | Wed, 20 Jun 2001 10:07:56 -0500 |
Content-Type: | text/plain |
Parts/Attachments: |
|
|
Chris wrote:
From our
hospital pharmacist I obtained the following information.
"Neurontin looks like a hard one to call, it has the low protein
binding but
the bioavailability of it drops as the dose goes up and the 800mg
tid is a
pretty hefty dose so I'm not sure what % of it is even bioavailable
to cross
into the milk. 76-81% of it is excreted by the kidneys which
indicates it
is fairly water soluble rather than lipid soluble further decreasing
the
amount we would suspect reaches the milk. While we don't know how
much
would pass into the milk, the type of effect would we expect to the
infant
is mostly CNS (sleepiness, dizziness, etc) so it may be worth a try
since
the benefit may outweigh this risk. There is dosing recommendations
for
kids as young as 3. Timing of the feeding just before a dose or at
least 3
hours after may help."
You must have "trained" this person well. So many would only
provide what's in PDR or some similarly "wonderous" source! It
sounds like this one is really knowledgable about what to really
consider in regards to meds in mother's milk.
Winnie
***********************************************
The LACTNET mailing list is powered by L-Soft's renowned
LISTSERV(R) list management software together with L-Soft's LSMTP(TM)
mailer for lightning fast mail delivery. For more information, go to:
http://www.lsoft.com/LISTSERV-powered.html
|
|
|