And maybe I’m old and a cynic, but I do NOT trust meta=analyses.  They are conflating several different studies, not conducted the same and trying to make them give better data.  Please read Frank Nice's paper on domperidone.  



-----Original Message-----

From: Lactation Information and Discussion [mailto:[log in to unmask]] On Behalf Of Laurie Wheeler

Sent: Thursday, December 10, 2015 9:52 PM

Subject: domperidone meta analyses



First, I am not very familiar with domperidone dosing nor use, as in my experience it is not used by local physicians and only rarely a mom obtains it. But, just wondering if the dosages are known with domperidone in those studies, and if the dose can be correlated with adverse cardiac events. Also the length of time a person is on said dosing. Also can’t this drug be given IV or PO and isn’t the IV dose more associated with cardiac events, and did the study look at route?

Just wondering.

Laurie Wheeler RN MN IBCLC

New Orleans LA and Mississippi Gulf Coast USA



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