Ann C.

Fludeoxyglucose is an analog of glucose that enters most all tissues of the
body according to their metabolic rate.  The radioactive ion 18(F),  has a
half-life of 110 minutes.   It would undoubtedly enter breast milk.

I would recommend to pump and discard milk after the procedure to reduce
radioactive exposure of the breast tissue.  The manufacturer recommends routine
bladder emptying for the same reason.   According to the USPDI(1982) the mother
should wait 12-24 hours before breastfeeding her infant.  In 9 hours,  97% of
the isotope will be decayed away.  Were the mother to pump and dump for 12
hours, and then feed her infant,  certainly most all of the radioactive
fluoride would be gone.


Tom Hale




FLUDEOXYGLUCOSE F 18 ((18)F) is         E.Clin Appl
       rapidly cleared from plasma after intravenous doses, and   F.Reference
       enters cells in a manner similar to glucose; it is         G.Author
       phosphorylated intracellularly by hexokinase to
       fludeoxyglucose F 18-6-phosphate but, unlike
       glucose-6-phosphate, is not metabolized further.  Uptake
       and accumulation of (18)F in tissues occurs in proportion
       to the rate of glucose metabolism, and this can be
       measured by PET; hypometabolism or hypermetabolism of      CUUP Up 1
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       glucose is characteristic of many diseases.  Uptake of     PREV Up 1
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       (18)F is greatest in the bladder wall, heart, spleen, and  NEXT Dn 1
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       brain.  Up to 20% of an intravenous dose of (18)F is       F11  Last
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       excreted in the urine within two hours.  The physical      F1   HELP
       half-life of (18)F is 110 minutes.