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Date: | Wed, 21 Oct 1998 22:03:17 -0400 |
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> Popular press books and articles about St. John's Wort never seem to fail to
> mention monoamine oxidase (MAO) inhibition with this herb, but this
> information is simply out-of-date.
>
I have never seen this reported in the popular press - at least not in
the US.
> Clinical experience of MDs in Germany, giving this herb to thousands of (
> adult ) patients, has shown that significant inhibition of MAO does not occur
> clinically, despite in vitro inhibition by the isolated constituent,
> hypericin. In vitro studies of single phytoconstituents are limited in what
> they can predict about the effects of the whole plant in vivo.
Dos anyone have any citations to support this? It has never been
suggested to me before that hypercin does not act as an MAOI in humans.
I would love to see reports on this since I am quite disturbed by the
number of depressed breastfeeding and pregnant women I see taking SJW
because they think herbs can not be harmful.
--
Jake Marcus-Cipolla, retired lawyer, student lactation
consultant, part-time media consultant (Marcus Media Consulting),
stay-at-home mom to Luca Antonio (7/26/94) and Nicholas Liam (5/1/97),
LLL Leader.
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