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Sat, 7 Mar 1998 08:38:56 +0100 |
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In my humble opinion, the risk is much more important for the foetus than
for the BF baby. It is teratogen or letal for the foetus in animals. Here,
pregnancy is strictly CI when it is taken.
Nothing about its passage in milk. But it is very poorly absorbed
by the gastrointestinal tract, more less when taken with food.
It is very highly bound to the plasmatic proteins (99%),
and it is also hyghly bound to the red cells. So, the passage in milk
is probably very low. Half live very variable : 3,5 to 40 hours
It is used in pediatric. Dose : 0,2-0,3 mg/kg/day per os, or
0,05 mg/kg/day IV.
Hope this help
Kindly
Francoise Railhet
LLL France Medical Associates Program
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