LACTNET Archives

Lactation Information and Discussion

LACTNET@COMMUNITY.LSOFT.COM

Options: Use Forum View

Use Monospaced Font
Show Text Part by Default
Show All Mail Headers

Message: [<< First] [< Prev] [Next >] [Last >>]
Topic: [<< First] [< Prev] [Next >] [Last >>]
Author: [<< First] [< Prev] [Next >] [Last >>]

Print Reply
Subject:
From:
Reply To:
Lactation Information and Discussion <[log in to unmask]>
Date:
Wed, 4 Feb 1998 21:04:51 +0000
Content-Type:
text/plain
Parts/Attachments:
text/plain (15 lines)
This is a benzodiazepine.  It has a long half life and relatively high,
but not extraordinarily high protein binding of about 80%.  It is well
absorbed from the gut.  It has active metabolites.  Taking all this into
consideration, it is probably not the benzodiazepine of choice to use
for a nursing mother, but it is probably okay.  Peak plasma levels in
mothers after taking 0.5 to 3 mg is reported as 8 to 37 *nano*grams/ml.
That's really low, and probably the baby will receive very insignificant
amounts.

Remember that benzodiazepines have even longer half lives in babies
under 1 month or so.  But we also use them to control seizures in very
small babies.

Jack Newman, MD, FRCPC

ATOM RSS1 RSS2