To : Pat Lindsey
Re : Parlodel (bromocriptine mesylate)
Bromocriptine is rapidly cleared from the body, with a high first-pass
uptake(94%) by the liver. Elimination half-life is about 6 hours. So almost
total clearance would be attained in 30 hours. Nevertheless, bromocriptine
passes into milk only poorly. One study has been reported of a mom receiving 5
mg/day for a pituitary tumor, with no untoward effects on the breastfed infant.
Oral bioavailability is poor, only 28% is orally absorbed. I seriously doubt
there would be any problem in this breastfeeding mother.
Regards
Tom Hale