Ione:

   from Dr. hale's book:

   ...following prenatal use, it has been found to produce a high rate of
depressed resiration, hypothermia, and feeding problems in newborns. newborns
were found to secrete lorasepam for up to 1 days postpartum. in one patient
receving 2.5 mg rwice daily for 5 days postpartum, the breastmilk levels were
12 ug/L. in another patient four hours after an oral dose of 3.5 mg. milk
levels averged 8.5 ug/L. simmerfield (1985) reports an average concentration
in milk of 9 ug/L and an average milk:plasma ratio of 0.22/ it would apprear
from these studies that the amount of l provided via milk would be clinically
insifnificant under most conditions.

   p. 244.


  briggs... " L has been used in labor to potentiate the effects of narcotic
analgesic. although not statistically significant, a higher incidence of
respiratory depression occurred in the exposed newborn infants. " p. 502

                  Patricia