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Date: | Tue, 11 Jun 1996 14:12:32 -0400 |
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Jo Mihalik (hi Jo!) asked about Flagyl. From Dr. Hale's "Medications and
Mother's Milk" -
Antibiotic, amebicide. Do not give during fist trimester of pregnancy, can
be mutagenic and carcinogenic. Following a 2 gm oral dose, milk levels were
reported to peak at 50-57 mg/L at 2 to 4 hours...milk levels after 24 hours
were approximately 10 mg/L. Following a dose of 250 mg three times daily,
the average milk level was 6 mg/L. For treating trichomoniasis, recommend 2
gm single oral dose, and discontinue breastfeeding for 24 hours, then
reinstitute. AHL = 8.5 hrs. PB = 10%. PHL = 25-75 hrs (full term infants).
AAP Reason for Concern.
Hope this helps.
Cathy Kaiser, LLLL
Franklin, TN
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