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Date: | Thu, 15 Feb 1996 09:23:26 -0600 |
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To : Sara C. Reuning
Re : Giardia
Nelson's pocketbook of pediatric antimicrobial therapy suggests
Furazolidone or metronidazole for giardia infections. Flagyl(metronidazole)
is generally preferred in the US today. However, the 2 gm STAT dose is
only recommended for vaginal trichonomiasis, NOT other infectious syndromes
such as giardia. The TID dosage for 7-8 days is generally required for
this syndrome. As to stopping breastfeeding during this exposure to
metronidazole, this is only slightly controversial, most clinicians let
the mom continue to breastfeed. Following a 250 mg dose TID, the average
milk concentration is only 6 mg/Liter of milk, far to low to harm and
infant.
We know very little about furazolidone, no data yet exists on its
concentration in breastmilk. I doubt it is any more effective than Flagyl,
with which we have a great deal of experience.
Tom Hale
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