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Date: | Sat, 7 Oct 1995 15:09:04 -0400 |
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Kellie:
omnipaque is found referenced in Dr. Hales' fourth edition:
page: 300
" radiopaque agents(except barium) are iodinated compounds uses to
visualize various organs during x-ray. cat scans and other radiological
procedures. These compounds are highly iodinated benzoic acid derivitives.
Although under usual circumstances, iodine produducts are contraindicated in
nursing mothers ( due to ion trapping in milk) these products are unique in
that they are extremely inert. According to the manufactures, less than
0.005% of the iodine is free. They are in essence pharacologically inert, not
metabolized, and are rapildly excreted by the kidney (80-90% within 24 hours)
They are known ot pass unchanged into human milk after IV administration.
They are not absorbed after oral administraion (<0.1% absorbtion) Although
most companies inserts suggest that infants be removed from the breast for 24
hours, no untoward effects have been reported with these products.
barium is a contrast agent, maternal absorption is limited. there have
been no reported harmful effects. (Dr. hale p.45)
I hope that Dr. Hale and the other pharmacologists will correct
me if this information is not accurate.
Neither of these is mentioned in Briggs or the pham section of
JHL
Hope this helps....
patricia
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