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Subject:
From:
Shirley Gross <[log in to unmask]>
Reply To:
Lactation Information and Discussion <[log in to unmask]>
Date:
Sun, 10 Sep 1995 02:48:04 GMT
Content-Type:
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For your query regarding bromocriptine, here is some information.

I am happy to report that bromocriptine is no longer indicated for the
supression of lactation in women in Canada.  Both Canadian manufacturers
have voluntarily complied and have removed this indication for their
product.  The action came after the media reported that the Food and Drug
Administration in the US had received 531 spontaneous adverse drug reation
reports in women of childbearing age since 1980 (including 32 reported
deaths, 31 strokes and 63 seizures).  In Canada we have not seen the same
degree of problems but our Health Protection Branch proceeded nevertheless.

They also suggested that there were other options available to mothers
including the use of cold packs, analgesics and COMPRESSION BANDAGES.  Sigh.
Two steps forward and one step back.

Bibliography:
CMAJ Jan. 1. 1995; 152(1)
U.S. Food and Drug Administration. FDA Medical Bulletin. Vol 24(2):
September 1994
Eickman FM.  Recurrant Myocardial Infarction in a postpartum patient
receiving bromocriptine.  Clin Cardiol 1992; 15:781-3
Meese MG et al.  Reassessment of bromocriptine use for lactation supression.
P and T 1992; 17:1003-4
Spalding G.  Bromocriptine (Parlodel) for supression of lactation.  Aust and
NZ J of Obs and Gynaecol 1991;31:344-45

Enjoy,

Dr. Shirley Gross  (from the great LACTNETTED north)
Director of the Edmonton Breastfeeding Clinic

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