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Date: | Fri, 6 Jan 2023 12:52:01 -0500 |
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1) not tested in the field. They explain why it can't be:
> Due to the highly contagious nature of AFB, hives cannot be challenged in the wild. Nor can bees (which are wild animals) be kept in captivity, as a single hive contains between 10,000 and 30,000 (in some cases up to 80,000) individual bees, who would need to fly out and forage in a radius of up to 10 km.
In other words, it has not been tested in the real world, with real hives and live AFB spores
2) nobody has shown how it works (if it does):
> While the insect’s immune system is lacking antibodies, it has been shown that they can prime themselves (immune priming). The mechanism behind this antibody-free immunological priming has been a mystery for a long time. The work done in honey bees established that information about the disease agent can be transferred to the next generation with the help of the egg yolk protein Vitellogenin carrying immune elicitors, such as pieces of bacteria.
"Information is transferred." That's about it. Could be proteins, dead spores, RNA, crumpled up notes under the table.
PLB
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