From Wikipedia:  "Methylenetetrahydrofolate reductase (MTHFR) is an enzyme that in humans is encoded by the MTHFR gene.[2] Methylenetetrahydrofolate reductase catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a cosubstrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.[3][4]"

Having two mutated genes has been associated with miscarriages (I found out I have one mutated gene when being worked up for early pg loss), but I'm not aware of any effects on lactation.

E. Spencer Joslin-Montlick, MD, BFUSA Counselor, Central CT 

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