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Date: | Tue, 8 Jun 2010 14:20:17 -0700 |
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I asked my husband, who has a doctorate in immunology, to take a quick
look at the breast cancer vaccine story. His response:
I reviewed the paper and although they have shown that inducing an
autoimmune response against a normal protein can reduce the incidence of
cancer in mice, my biggest concern with this type of approach is
specificity of the immune response. Unfortunately this is
subject to errors in a living system. The T cell response is fairly
specific to peptides within the original target protein but not
absolutely perfect. Over time or in certain individuals, the specificity
of the immune response could vary and result in a reaction against
other albumin proteins in the body. This could be very serious indeed.
I think this treatment would be valid for high risk women past
childbearing age but it will be another 10 years before we see this type
of therapy available.
Arly Helm, MS, IBCLC
It's springtime in the Sierras!
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