Morgan

Many thanks for this question, and thank you for 
your kind words about the WABA World AIDS Day 
Statement.  Sorry, I was in the air on 1 
December, flying to WABA in Penang, and have only 
just caught up to it (going backwards through unread LACTNETS!).

Are you asking about the studies which show that 
exclusive breastfeeding for HIV-exposed babies 
carries a far lower risk of transmission (0-4% in 
the first 6 months, ~5-6% by 15-18 months) than 
mixed breast and other-milk feeding (or mixed 
feeding with other foods and liquids before 6 
months) where the risk is ~14-16% over two 
years??  If so, there are four studies which look 
at this, although the first and second cited 
below only followed infants to 6 months.

Coovadia HM, Rollins NC, Bland RM, Little K, 
Coutsoudis A, Bennish ML, Newell 
M-L.  Mother-to-child transmission of HIV-1 
infection during exclusive breastfeeding in the 
first 6 months of life: an intervention cohort 
study. Lancet 2007 March 31;369:1107-16.

Coutsoudis A, Pillay K, Spooner E, Kuhn L, 
Coovadia HM.     Influence of infant-feeding 
patterns on early mother-to-child transmission of 
HIV-1 in Durban, South Africa: a prospective 
cohort study. South African Vitamin A Study 
Group. Lancet. 1999 Aug 7;354(9177):471-6.

Coutsoudis A, Pillay K, Kuhn L, Spooner E, Tsai 
W-Y, Coovadia HM for the South African Vitamin A 
Study Group.  Method of feeding and transmission 
of HIV-1 from mothers to children by 15 months of 
age: prospective cohort study from Durban, South Africa.  AIDS 2001;15:379-387

Iliff PJ, Piwoz EG, Tavengwa NV, Zunguza CD, 
Marinda ET, Nathoo KJ, Moulton LH, Ward BJ, the 
ZVITAMBO study group and Humphrey JH. Early 
exclusive breastfeeding reduces the risk of 
postnatal HIV-1 transmission and increases 
HIV-free survival. AIDS 2005, 19:699–708.

If this wasn't the info you were hoping to source, please let me know.

Pamela (Morrison)
Co-coordinator WABA Breastfeeding and HIV Task Force


At 05:00 02/12/2007, you wrote:
>Date:    Sat, 1 Dec 2007 17:14:25 +0000
>From:    Morgan Gallagher <[log in to unmask]>
>Subject: HIV & breastfeeding babies
>
>A little while ago in here, there was a discussion that HIV+ infection
>with formula feeding babies was higher than breastfeeding ones, which
>was presumed to be about the gut irritation and close proximity to the
>virus via the mother. (Versus the protective nature of the milk on the
>gut, in reducing the transfer of the virus directly).
>
>This isn't mentioned in the excellent WABA release from today, World
>AIDS day, that Pamela posted earlier.
>
>Does anyone have a cite or reference to this, or am I
>hallucinating/misremembering?
>
>Many Thanks
>
>Morgan

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