My post to the list asking what else besides not breastfeeding ones
child(ren) could contribute to the high rates of breast cancer instigated a
lot of responses.
This is another response sent recently. It gives a plausible hypothesis in
the realm of chemical exposure to fluoride, just as the Philadelphia Times
Herald editorial questioned regarding water fluoridation. New knowledge of
simply having been breastfed being of some protection, then it would seem
that feeding AIM made with fluoridated water is magnifying cancer risks in
adulthood to the child who received that artificial milk.
Judy Ritchie
A plausible hypothesis about why fluoride could cause breast cancer. From
Maureen Jones:
Water Fluoridation, Melatonin, and Breast Cancer
The human pineal gland avidly attracts fluoride from the bloodstream.
Melatonin, the main pineal hormone, has several putative functions including
suppression of the age of sexual maturation in experimental animals.
Research by J. Luke at the University of Surrey, England in 1994 found that
fluoride inhibits pineal gland melatonin synthesis in the immature gerbil.
In his book, Breast Health, Princeton oncologist Dr. Charles Simone writes,
"low levels of melatonin have been linked to breast cancer as well as
prostate cancer."
Evidence from rodent studies found that pinealectomy increased tumor growth,
that administration of melatonin inhibited the promotion of chemically
induced mammary tumors, and that constant light exposure had a
growth-promoting effect on chemically induced tumors.
In humans, impaired pineal secretion of melatonin is associated with an
increased release of estrogen by the ovaries, and low serum melatonin
concentrations have been linked with estrogen receptor positive breast
cancer. In vitro, physiologic concentrations of melatonin inhibited the
growth of human breast cancer cell.
Peak melatonin levels normally occur during sleep in the middle of the
night.
In 2001, the Journal of the National Cancer Institute, (Vol. 93, No. 20,
October 17) published two studies: The case-control study by Davis et al.
found that graveyard shift work was associated with a 60% increase in breast
cancer risk. The prospective study by Schernhammer et al. found that nurses
who had performed nightshift work for between 1 and 29 years showed an 8%
increase in relative risk of breast cancer, and nurses with at least 30
years of nightshift work showed a 36% increase in relative risk.
Positive associations between shiftwork and breast cancer risk were also
observed in three smaller cohort studies, and indirect support for the
melatonin hypothesis comes from studies on blind women whose melatonin
levels do not change but show a 20% to 50% reduced risk of breast cancer
with an inverse dose-response relationship between degree of blindness and
breast cancer risk.
While the editorial of the NCI Journal finds the results of these recent
studies "alarming" and concludes there is an "urgent need for further
exploration" of cancers that may be influenced by melatonin, it is clear
that until these studies are done, based on the precautionary principal
alone, an immediate nationwide moratorium of water fluoridation is warranted
due to fluoride's known ability to inhibit melatonin syntheses in laboratory
animals.
-------------------------------------------------
More info on Luke's work on the Pineal gland
http://www.fluoridealert.org/ifin-269.htm
http://www.fluoridealert.org/health/pineal/
Melatonin slows breast cancer
http://www.webmd.com/content/article/71/81159.htm
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