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Date: | Wed, 20 Jul 2005 17:00:25 -0500 |
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Intrapartum antibiotics predispose to nursing-linked yeast infection
Source: Obstetrics & Gynecology 2005; 106: 19-22
Estimating whether the receipt of intrapartum antibiotics increases the risk
of neonatal thrush or maternal breast infections in nursing mother-infant
pairs.
Use of intrapartum antibiotics appears to raise the risk of thrush and
breast candidiasis in nursing infant-mother pairs, researchers warn.
In addition to the well-recognized role of antibiotics in the development of
vaginal candidiasis, there is some evidence to suggest that such treatment
during the postpartum period influences nipple candidiasis, notes Mara
Dinsmoor, from the Medical College of Virginia Hospital in Richmond, USA,
and her team.
To investigate whether intrapartum antibiotic therapy influences the risk of
neonatal thrush and maternal breast infections, they analyzed follow-up data
for 435 mother-infant pairs who nursed for 1 month or longer. Among these
new-mothers, 173 (39.8 percent) received intrapartum antibiotics, mostly for
group A streptococci prophylaxis.
Within 1 month of delivery, thrush or breast candidiasis were detected in 46
(10.6 percent) mother-infant pairs. Both the breast and oral infection were
more common in individuals exposed to antibiotics postpartum, with odds
ratios of 2.1 and 1.87, respectively; however, only the former relationship
reached statistical significance.
Dinsmoor and co-authors say their findings, if confirmed in larger studies,
warrant "further investigation into methods to reduce the risk of postnatal
yeast infections."
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