http://www.medscape.com/viewarticle/468412

"To our knowledge, this is the first careful documentation of intake of
live bacteria over any extended period of time in any population. The
intakes studied can be used as a benchmark for well-tolerated, safe intake
of these bacterial agents," the authors write. "Long-term consumption of
formulas supplemented with B. lactis and S. thermophilus was well tolerated
and safe and resulted in adequate growth, reduced reporting of colic or
irritability, and a lower frequency of antibiotic use."

Nestlé USA supported this study and provided formulas.

Am J Clin Nutr. 2004;79:261-267

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