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Subject:
From:
Judy Ritchie <[log in to unmask]>
Reply To:
Lactation Information and Discussion <[log in to unmask]>
Date:
Sun, 18 Apr 2004 23:05:58 -0700
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Ann posted this reference:  http://biochem.uwa.edu.au/PEH/PEHres.html
PRINCIPAL FINDINGS
1. The concentration of prolactin in the maternal plasma does not control
milk synthesis. 
7. The control of milk synthesis may restrict the binding and entry of
prolactin into the cell.


From a study posted to the www.Celiac.com
list there is another finding regarding elevated serum prolactin.  This
study was done on children, but later paragraph states it is a valuable test
for patients, which I interpret to mean all ages.
Judy Ritchie

Elevated Levels of Serum Prolactin Linked to Celiac Disease
  
J Tropical Pediatrics 2004, 50:37-40
Celiac.com 03/30/2004 - Researchers in India have discovered that serum
prolactin levels in those with celiac disease are elevated in direct
proportion to the severity of the disease. Dr. Gaurav Kapur and colleagues
from the Lady Hardinge Medical College, New Delhi screened serum prolactin
levels in 41 children who were diagnosed with celiac disease, 21 of which
were on a gluten-free diet for more than a year. The results were compared
to 41 healthy controls. The researchers found that serum prolactin levels
were highly elevated in those with active celiac disease (average of 48.3
ng/mL), and present at lower levels in those on a gluten-free diet (average
of 18.3 ng/mL). The healthy controls had an average level of 9.3 ng/mL. The
longer the disease was left untreated along with the increase in severity of
villous atrophy, the higher the levels of serum prolactin that were
detected.

The researchers conclude that serum prolactin levels can be used to
determine the severity of celiac disease in patients, and this option is
more economically viable than the use of other options. 
 



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