If I remember the research I did for a paper in my mental health nursing
course correctly, the SSRI's are generally considered "safe" for use during
lactation. However, the guidlines I read recommended, among other things,
using TCA's (or SSRI's) if possible, using one medication rather multiple
medications for tx of depression in lactating mothers (not a problem in this
case presumably?), pumping and dumping @ times when the concentration of the
drug in the breastmilk is @ its highest (Hale's book and other breastfeeding
and medication drug guides usually have this information) if the drug is
deemed to be potentially harmful to the nursing child, monitoring the child's
serum blood levels of the drug and its metabolites @ regular intervals, and
closely monitoring for adverse effects in the child (i.e., serotonin
syndrome). A major problem identified in a Cochrane review of antidepressant
use during lactation is the relative lack of RCT's and the tendency towards
small sample sizes in many of the existing studies. I think that this explains
some of the fence-sitting you describe.
BTW, I can dig up my references if anyone is interested.
Dru Antoniuk
B.A., M.A., current B.Sc.N student, aspiring LC/midwife, mother to two
wonderful (and breastfed) little girls
>Date: Mon, 21 Jul 2003 13:48:44 -0700
>From: Brenda Phipps <[log in to unmask]>
>Subject: Mom on Celexa with preemie
>
>I have a mother taking 10 mg of Celexa per day. The usual dose is 20 mg.
>Baby is 33 week preemie in SCN. Mother is concerned about effects of the
>drug because her baby is so small. Pediatrician is riding the fence, and
>not sure as well.
>
>Have any of you experienced negative outcomes in the preemie when
>mother is on this drug? Hale's book classifies it is an L#, and in
>archived posts he states h=it should be perfectly fine, but for an
>8-month old.
>
>Thanks!
>Brenda Phipps, BS, IBCLC
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