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Date: | Wed, 12 Mar 2003 13:46:03 EST |
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Of interest is the following quote from the 8th International Pacific Rim
Biotechnology Conference 2002. I recognize that there are many on this list
that may think that transgenics hasn't happened yet. So thought this worth
reading for the skeptics and anyone else who has an interest. Valerie W.
McClain, IBCLC
http://www.biotech.org.nz/confernc.htm
"The interface between agricultural biotechnology and human therapeutics was
explored by Stewart Washer from Celentis, a company which commercialises
research from the crown research institute, AgResearch. Using transgenic
animals to produce protein therapeutics has already been successful, with the
first targets already produced. The demand for protein-based therapeutics
will outstrip the supply. It is estimated that up to 30% of new products
developed will utilise alternative technologies. Mammalian cell culture and
transgenic animals are the two techniques that can currently be used to
produce complex proteins. However, there is a cost benefit on the side of
transgenics, with the investment and production costs for a herd of cattle
being 1-2% of those for a mammalian cell culture plant. Purification costs
for products from both methods of production are similar. The FDA sees New
Zealand as a popular choice for the use of transgenic animals as animal
bioreactors because of its BSE-free status. Celentis is also interested in
drug delivery systems, particularly those that would improve the safety,
efficiency and the cost of treatments. Two controlled release products are
currently on the market – TimeCapsule (TM) and SmartShot (TM) for animal
health. Currently under development is milk with increased levels of
immunoglobulin A, which would assist in boosting the immune system against
human pathogens. The interface between agricultural and medical biotechnology
allows the strong capability in agriculture to impact on medical
biotechnology, whilst the large R&D spend on medical research benefits the
agricultural industry. The final business session of the day provided an
interesting mix of technology transfer, spin out companies, venture capital
and developments in health research."
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