thanks Cathy
I can get the abstract online but not the full text at
http://www3.oup.co.uk/humupd/hdb/Volume_06/Issue_04/060374.sgm.abs.html
here it is cut & pasted:
Human Reproduction Update, Volume 06, Issue 4, pp. 374-386: Abstract.
Breastfeeding and risk of breast cancer: a meta-analysis of published
studies
M. O. Bernier1, G. Plu-Bureau1, N. Bossard2, L. Ayzac3, and J. C.
Thalabard1, 4
Corresponding author: J. C. Thalabard, Medecine de la Reproduction, Pavillon
Apert, Hôpital Necker, 149, rue de Se(c)vres, 75743 Paris cedex 15, France.
Phone: +33 144 49 43 91; Fax: +33 144 49 25 58; e-mail: [log in to unmask]
1Department of Reproductive Medicine, Hopital Necker, Paris,
2Department of Biostatistics, Centre Hospitalier Lyon-Sud, Pierre Benite,
3Department of Hygiene and Public Health, Centre Hospitalier Lyon-Sud,
Pierre Benite,
4Laboratory for Biostatistics, University Paris V, UFR Necker-Enfants
Malades, Paris, France
Evidence in favour of an association of breastfeeding with a breast cancer
risk reduction remains limited and inconsistent. To evaluate the relation
between breastfeeding and breast cancer, a meta-analysis based on a review
of the literature was carried out, using as variables ever/never
breastfeeding and duration of breastfeeding. Menopausal status at the time
of diagnosis of breast cancer was considered to be a potential effect
modifier. Only case-control studies could be included in the final analysis.
A slight but significant decreased risk of breast cancer was observed in
ever breastfeeding, compared with never breastfeeding parous women, using
both the fixed and random-effect models. This decrease was more pronounced
in non-menopausal women at the time of diagnosis of breast cancer and in
long-term breastfeeding women. Hence, breastfeeding appeared to be a
protective factor but was of small magnitude compared with other known risk
factors for breast cancer. Whether this result should imply a modification
in the attitude of both health care providers and women towards
breastfeeding, which represents one of the few identified protective factors
which is under the control of the mother, and is thus (theoretically)
modifiable, remains questionable.
Keywords: Breastfeeding, breast cancer, meta-analysis, epidemiological
methods
Regards
Karen Clements IBCLC
Melb Aust
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