>.It's difficult to sort out whether this edema is a direct result of the
pitocin itself, or is somehow related to the overhydration that results
from its dilution for infusion, or combined with overhydration
deliberately administered before the epidural.<<

It was my understanding that the edema would result from upregulation of ADH
receptors, which would cause a greater response to circulating ADH. Greater
response = more conservation of water. I would assume that overhydration
would be on top of this.

>>The mystery seems to be why this infused oxytocin does not result in an
MER effect so that more is available at the front of the breast after
delivery.<<

I touched on this with Dr. Craig as we discussed syntocinon. Some is good,
too much is bad. I'm recalling what we've heard about rebound effect with
syntocinon.....

Lisa

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