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Subject:	Re: DWV test results for Newfoundland bee stock
From:	Peter Borst <[log in to unmask]>
Reply To:	Informed Discussion of Beekeeping Issues and Bee Biology <[log in to unmask]>
Date:	Wed, 18 Oct 2017 14:04:43 -0400
Content-Type:	text/plain
Parts/Attachments:	text/plain (10 lines)

Hi there
As you noted, genomic tests are plagued by false positives, false negatives, as well as incorrect probes. To make matters worse, viruses are mutating all the time and can exchange DNA with each other. This is explained in great detail (more than I can digest in one meal): 

Robert Scott Cornman. Relative abundance of deformed wing virus, Varroa destructor virus 1, and their recombinants in honey bees (Apis mellifera) assessed by kmer analysis of public RNA-Seq data. Journal of Invertebrate Pathology 149 (2017) 44–50

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