With all due respect, no.  I'm not a good chemist, Dick (meaning that's not my degree, and I have to think hard about chemistry), but I am a decent physiologist.  The conditions in the synapse preclude any useful degradation of the bond between the neonic and the receptor, because the binding coefficient of the neonic is so much greater than that of the native acetylcholinesterase that there is no contest.  That translates to "irreversible", given ambient conditions and lifespan of the bee.

Christina


You are absolutely fundamentally wrong.  You completely ignore relative concentrations, diffusion, and the basic physics.  Neonics are NOT irreversible.  Neonics are low nanomolar binders of honeybee nicotinic acetylcholine receptors THAT IS NOWHERE NEAR irreversible.   Even worse, you dismiss research that clearly shows you are wrong even though you admit that you are well outside of your field of expertise... 

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