What a very special situation this is, one sister having a baby for the other! Have you thought of manual expression instead of pumping (more skin to skin stimulation, more like "the real thing" and easier to catch those precious first few drops in a small cup than on the larger surface area of a pump). I have worked with a couple of adoptive moms who had some success with gentle breast massage, then manual expression, minimum 8 times/24 hours and medication with sulpiride (similar to metoclopramide) 50 mg three times/day to raise prolactin levels. Other things which I feel sure will help are lots of physical cossetting and spoiling, e g massage all over, long luxurious baths, loving touch by husband - anything which makes prospective mother feel warm and special and female. Best wishes, please keep us informed. Pamela Morrison IBCLC, Zimbabwe